December 8, 2013
PHGH is a male enhancement pill developed and sold by adult-film star John Lawrence. The pill has been featured in Men’s Health and Ask Men and is touted as “the most effective and highest-quality product on the market.” 
I stripped PHGH down to its ingredients, the amounts used, and if they’re effective. I’ll share what I found.
Lawrence’s claim is his product uses natural ingredients to increase blood flow, resulting in the hardest possible erection. Unlike other male enhancement manufacturers, Lawrence doesn’t say the product will just increase penis size and girth, but that each man will reach his full capacity with maximum blood flow, hardness and size.
He states, “PHGH was designed to do only one thing: maximize blood flow. Because that’s what makes our erections harder.” 
PHGH uses a proprietary blend, which usually means the ingredient amounts aren’t listed. Surprisingly, the dosages of all eleven ingredients in the blend are available.
This is promising because it shows the company isn’t trying to hide behind a “special formula.”
Arginine is the first and most abundant ingredient; PHGH contains almost as much arginine as the other 10 ingredients combined. While most male enhancements, including Viagra, use PDE-5 inhibitors, PHGH’s main ingredient is arginine.
Studies have shown arginine increases nitric oxide production and relaxes smooth muscle fibers. The result is more blood flow and muscle relaxation to areas controlled smooth muscle, such as the penis.   Basically, arginine pushes more blood into the penis for a harder, larger erection.
Subjects with mild erectile dysfunction in another study experienced improved erection hardness with 750 mg arginine daily.  PHGH provides 500 mg arginine in two capsules, so users should experience increased erection hardness.
Tribulus terrestris is a popular ingredient in many testosterone boosters, which is probably why it’s the second most plentiful ingredient in PHGH, at 200 mg per dose. While increased testosterone leads to greater libido, research is divided on tribulus terrestris’ effects.
Tribulus terrestris been shown to be effective for increasing erections in rabbits, rats, and primates, but it may not be as effective in humans. Other research indicates there may be a greater effect in older men with lower testosterone levels than in younger males.   
The tribulus terrestris amount in PHGH is more than that used in studies that reported positive results. The ingredient works for some men, and PHGH contains enough to be effective in those cases.
Lawrence calls tongkat ali (eurycoma longifolia) “an ancient and mysterious root that grows in the jungles of Indonesia … One of the most potent elements in any male enhancement.” 
Tongkat ali, Also called Malaysian ginseng, is a medicinal plant traditionally used as an aphrodisiac. Resent research supports the traditional use as a libido and testosterone booster and shows the plant is also effective at lowering stress levels.   
PHGH contains 100 mg tongkat ali per dose, significantly less than the 400 mg used in effective studies. This doesn’t mean the ingredient is ineffective, but the results may be less significant than those reached in clinical research.
L-Carnitine has effects similar to those of arginine. Studies examining L-carnitine found it is effective at treating erectile dysfunction when used with other ingredients such and L-arginine. 
Catuaba bark comes from a tree native to Brazil and is supposedly used by native tribes as a male enhancement: “Catuaba” means “what gives strength to the Indian. Unfortunately, I was unable to find any evidence that it is effective for penile enhancement.
Epimedium (horny goat weed) is effective because it contains icariin, which is a mild PDE-5 inhibitor. Studies show it effectively increases blood flow to the penis and may slightly raise testosterone levels and libido. 
PHGH has 20 mg epimedium, more than most effective studies use.
Gingko Biloba and Maca and DHEA are less prevalent ingredients in PHGH, but several studies have been published showing their effectiveness in treating erectile dysfunction and stress levels. The effects may be diminished because of PHGH’s small doses, but the benefits are legitimate. 
Muira Puama is another Amazonian plant. While some individuals claim it is useful for treating sexual disorders, I was unable to find any solid evidence of its effects. 
Piperina (Bioperine) is responsible for the potency of black pepper. Used in supplements, it increases the effects of the other ingredients. 
Price and Availability
Each 60-count bottle of PHGH contains 30 days of servings. One bottle is available from $39.95, two bottles for $67, and three bottles for $89. In addition, the company offers a 60-day money-back guarantee. 
Taking it down to just the ingredients, PHGH seems like a decent product. I really like that they provide the amounts in the proprietary blend; that’s not common and lends an air of legitimacy to their claims. The main ingredients are effective at increasing blood flow and testosterone and should enhance erection size, hardness, and length. However, some of the ingredients aren’t proven to be effective. They are included in very small amounts but are still there.
All in all, I like PHGH. The company is open about its ingredient amounts, and the price is comparable to other male enhancement supplements, with discounts for larger orders. The only thing I dislike is the non-proven ingredients.
3.5 out of 5 stars
 PHGH. Phgh.com. Available from: http://phghrx.co/index.html
 FAQ. PHGH.com. Available from: http://phghrx.com/faq.html
 Valente EG, et al. http://www.ncbi.nlm.nih.gov/pubmed/14996430 Nitric Oxide. 2003 Dec;9(4):229-44.
 Cartedge J, et al. “The role of nitric oxide in penile erection.” Expert Opinion of Pharmacotherapy. 2001 Jan;2(1):95-107. Available from: http://www.ncbi.nlm.nih.gov/pubmed/11336572
 Cormio L, et al. “Oral L-citrulline supplementation improves erection hardness in men with mild erectile dysfunction.” Urology. 2011 Jan;77(1):119-22. Available from: http://www.ncbi.nlm.nih.gov/pubmed/21195829
 Gauthaman k, Ganesan AP. “The hormonal effects of Tribulus terrestris and its role in the management of male erectile dysfunction–an evaluation using primates, rabbit and rat.” Phytomedicine. 2008 Jan;15(1-2):44-54. Available from: http://www.ncbi.nlm.nih.gov/pubmed/18068966
 Jungmo Do, et al. “Effects and Mechanism of Action of a Tribulus terrestris Extract on Penile Erection.” Korean Journal of Urology. 2013 Mar;54(3):183-188. Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3604572
 Neychev VK, Mitev VI. “The aphrodisiac herb Tribulus terrestris does not influence the androgen production in young men.” Journal of Ethnopharmacology. 2005 Oct 3;101(1-3):319-23. Available from: http://www.ncbi.nlm.nih.gov/pubmed/15994038
 Ang HH, Cheang HS. “Effects of Eurycoma longifolia jack on laevator ani muscle in both uncastrated and testosterone-stimulated castrated intact male rats.” Archives of Pharmacal Research. 2001 Oct;24(5):437-40. Available from: http://www.ncbi.nlm.nih.gov/pubmed/11693547
 Henkel, et al. “Tongkat Ali as a Potential Herbal Supplement for Physically Active Male and Female Seniors-A Pilot Study.” Phytotherapy Research. 2013 Jun 11. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23754792
 Talbott SM, et al. “Effect of Tongkat Ali on stress hormones and psychological mood state in moderately stressed subjects” Journal of International Sports Nutrition. 2013; 10: 28. Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669033
 Gentile V, et al. “Effect of propionyl-L-carnitine, L-arginine and nicotinic acid on the efficacy of vardenafil in the treatment of erectile dysfunction in diabetes.” Current Medical Research and Opinion. 2009 Sep;25(9):2223-8. Available from: http://www.ncbi.nlm.nih.gov/pubmed/19624286
 Shindel AW, et al. “Erectogenic and neurotrophic effects of icariin, a purified extract of horny goat weed (Epimedium spp.) in vitro and in vivo.” Journal of Sexual Medicine. 2010 Apr;7(4 Pt 1):1518-28. Available from: http://www.ncbi.nlm.nih.gov/pubmed/20141584
 Chen KK, Chiu JH. “Effect of Epimedium brevicornum Maxim extract on elicitation of penile erection in the rat.” Urology. 2006 Mar;67(3):631-5. Available from: http://www.ncbi.nlm.nih.gov/pubmed/16527595
 MacKay, Douglas. “Nutrients and Botanicals for Erectile Dysfunction: Examining the Evidence.” Altrenative Medicine Review. 2004; 1(9)4-16. Available from: http://www.altmedrev.com/publications/9/1/4.pdf
 Foster S, Tyler VE. Tyler’s Honest Herbal: A Sensible Guide to the Use of Herbs and Related Remedies. 3rd ed., Binghamton, NY: Haworth Herbal Press, 1993.
 McNamara FN, et al. “Effects of piperine, the pungent component of black pepper, at the human vanilloid receptor.” British Journal of Pharmacology. 2005 March; 144(6): 781–790. Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1576058
 Order. PHGH.com. Available from: http://phghrx.com/order.html